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atomoxetine hydrochloride

The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft; the effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.
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Synonym:tomoxetine
US brand name:Strattera
Chemical structure:(-)-N -methyl-3-phenyl-3-(o-tolyloxy)-propylamine hydrochloride
(-)-N-methyl-gamma(2-methylphenoxy)benzenepropamine Hydrochloride
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