autologous anti-CD19 CAR-expressing T lymphocytes CLIC-1901
A preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) that targets the human tumor associated antigen (TAA) CD19, with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR-expressing T lymphocytes CLIC-1901 bind to and induce selective toxicity against CD19-expressing tumor cells. The CD19 antigen is a B-cell-specific cell surface antigen expressed in all B-cell lineage malignancies.
Synonym: | autologous CLIC-1901 CAR-T cells |
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Code name: | CLIC 1901 CLIC-1901 CLIC1901 |