autologous anti-CD5 CAR T lymphocytes MB-105
A preparation of genetically modified autologous T cells expressing a chimeric antigen receptor (CAR) directed against cluster of differentiation 5 (CD5), with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-CD5 CAR T lymphocytes MB-105 target and bind to CD5-expressing tumor cells, thereby inducing selective cytotoxicity in CD5-expressing tumor cells. CD5 is a T-cell surface glycoprotein expressed on the surface of normal T cells and overexpressed on various B- and T-cell malignancies.
| Synonym: | autologous anti-CD5 CAR T cells MB-105 autologous anti-CD5 CAR-T cells MB-105 autologous CD5-specific CAR T cells MB-105 autologous CD5-targeted CAR-T cells MB-105 autologous CD5CAR-expressing T lymphocytes MB-105 |
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| Code name: | MB 105 MB-105 MB105 |