autologous anti-EBV CAR T cells BRG01
A preparation of autologous T lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) targeting an Epstein-Barr virus (EBV) protein, with potential immunostimulating and antineoplastic activities. Upon intravenous administration, the autologous anti-EBV CAR T cells BRG01 targets a specific EBV protein expressed on EBV-positive cancer cells and promotes killing of these cancer cells. EBV infection is associated with various cancers and the expression of certain EBV specific proteins plays a key role in tumor cell proliferation and survival.
Synonym: | autologous anti-EBV CAR-T cells BRG01 |
---|---|
Code name: | BRG 01 BRG-01 BRG01 |