autologous anti-gp100:154-162 TCR tumor infiltrating lymphocytes
A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for the amino acid 154 through 162 of the melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activities. Upon intravenous administration, the autologous anti-gp100:154-162 TCR TILs may recognize and halt the growth of gp100-expressing melanoma cells.
| Synonym: | autologous anti-gp 100:154-162 TCR TILs autologous anti-gp100:154-162 TCR gene engineered TILs autologous anti-gp100:154-162 TCR gene-engineered tumor infiltrating lymphocytes autologous anti-gp100:154-162 TCR TILs autologous anti-gp100:154-162 TCR-engineered TILs |
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