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autologous anti-GPC3 CAR T lymphocytes JWAT204

A preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for glypican-3 (GPC3), with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-GPC3 CAR T lymphocytes JWAT204 specifically target and bind to GPC3-expressing tumor cells, resulting in tumor cell lysis. GPC3, a heparan sulfate proteoglycan and a member of the glypican family, is overexpressed on certain tumor cell types while minimally expressed in normal, healthy cells; GPC3 plays an important role in cellular proliferation and differentiation.
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Synonym:autologous anti-GPC3 CAR T cells JWAT204
autologous anti-GPC3 CAR-T cells JWAT204
autologous CAR-GPC3 T cells JWAT204
autologous GPC3-directed CAR-T cells JWAT204
Code name:JWAT 204
JWAT-204
JWAT204
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