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autologous anti-mesothelin CAR-T cells UCLM802

A preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the human tumor-associated antigen (TAA) mesothelin (MSLN), with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-MSLN CAR-T cells UCLM802 specifically target and kill MSLN-expressing tumor cells. Mesothelin, a cell surface glycoprotein involved in cell adhesion, is overexpressed in a variety of cancer cell types.

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Synonym:	autologous anti-MSLN CAR-T cells UCLM802
Code name:	UCLM 802 UCLM-802 UCLM802

autologous anti-mesothelin CAR-T cells UCLM802

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