autologous GPC3/NY-ESO-1/AFP-specific CD8-positive T lymphocytes
A preparation of autologous CD8-positive T lymphocytes that are exposed, ex vivo, to multiple specific hepatocellular carcinoma (HCC) antigens, including glypican (GPC)-3, New York esophageal squamous cell carcinoma-1 (NY-ESO-1) and alpha-fetoprotein (AFP), with potential immunostimulating and antineoplastic activities. Upon infusion of the GPC3/NY-ESO-1/AFP-specific CD8-positive T lymphocytes, the T cells specifically target and lyse cells expressing the targeted HCC neoantigens.
| Synonym: | autologous HCC antigens-specific CD8-positive T lymphocytes autologous HCC antigens-specific CD8+ T lymphocytes autologous specific HCC antigens CD8+ T cells |
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