autologous HPV-specific cytotoxic T lymphocytes
A population of autologous cytotoxic T lymphocytes (CTLs) that are specifically reactive to human papillomavirus (HPV), with potential antiviral and antineoplastic activities. Upon infusion of the autologous HPV-specific CTLs, these CTLs induce selective toxicity in HPV-positive cancer cells and other HPV-infected cells. HPV is associated with various cancer cell types.
Synonym: | autologous HPV-specific immune lymphocytes |
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Abbreviation: | autologous HPV-CTLs |