autologous HPV16/HPV18/Survivin-specific CD8+ T cells NEXI-003
A preparation of autologous CD3+ CD4- CD8+ T cells targeting multiple human papilloma virus (HPV) tumor-associated antigens, including HPV types 16 and 18 antigens and survivin, with potential immunomodulating and antineoplastic activities. Following leukapheresis and ex vivo priming and expansion, the autologous HPV16/HPV18/survivin-specific CD8+ T cells NEXI-003 are re-introduced into the patient, where they target and kill tumor cells expressing these HPV tumor-associated antigens.
Synonym: | autologous HPV tumor-relevant antigen-specific CD8+ T cells NEXI-003 CD3+ CD4- CD8+ T cells NEXI-003 |
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Code name: | NEXI 003 NEXI-003 NEXI003 |