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autologous monocyte-derived lysate-pulsed dendritic cells PV-001-DC

A cell-based cancer vaccine composed of autologous, monocyte-derived dendritic cells (mDCs) pulsed with tumor cell lysate containing tumor associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration,the autologous tumor cell lysate-pulsed mDCs vaccine PV-001-DC may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the patient's tumor cell-specific TAAs, which may result in tumor cell lysis.
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Synonym:autologous monocyte-derived lysate pulsed DCs PV-001-DC
PV-001-dendritic cell
Code name:PV-001-DC
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