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azimexon

Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma.
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Synonym:azimexone
Abbreviation:AZ
Code name:BM 12.531
BM12531
Chemical structure:2-aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl]
2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane
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