azimexon
Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma.
| Synonym: | azimexone |
|---|---|
| Abbreviation: | AZ |
| Code name: | BM 12.531 BM12531 |
| Chemical structure: | 2-aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl] 2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane |