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buserelin

A synthetic analog of gonadotropin-releasing hormone (GnRH). Buserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids. Buserelin is more potent that GnRH.
Synonym:buserelin acetate
busereline
US brand name:Etilamide
Foreign brand name:Bigonist
Profact
Profact Depot
Receptal
Suprecur
Suprefact
Suprefact Depot
Suprefact Flakon
Abbreviation:BSRL
Code name:HOE 766
ICI 123215
S74-6766
Chemical structure:6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide luteinizing hormone-releasing factor (pig)
D-ser (bu(t))(6) pro(9) NEt LHRH Acetate
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