buserelin
A synthetic analog of gonadotropin-releasing hormone (GnRH). Buserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids. Buserelin is more potent that GnRH.
| Synonym: | buserelin acetate busereline |
|---|---|
| US brand name: | Etilamide |
| Foreign brand name: | Bigonist Profact Profact Depot Receptal Suprecur Suprefact Suprefact Depot Suprefact Flakon |
| Abbreviation: | BSRL |
| Code name: | HOE 766 ICI 123215 S74-6766 |
| Chemical structure: | 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide luteinizing hormone-releasing factor (pig) D-ser (bu(t))(6) pro(9) NEt LHRH Acetate |