camsirubicin
A synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Camsirubicin intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis.
| Code name: | GPX-150 GPX150 |
|---|---|
| Chemical structure: | 5-imino-13-deoxydoxoubicin |