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CD56-enriched CD3-positive donor lymphocytes

A population of CD3-positive lymphocytes expressing the CD56 surface antigen, with potential immunomodulating activity. Upon infusion of the CD56-enriched CD3-positive donor lymphocytes, these cells may facilitate the reconstitution of CD4-positive T cells, regulatory T cells (Tregs) and natural killer (NK) cells, which may reduce the incidence of post-transplant graft-versus-host disease (GvHD) following haploidentical stem cell transplant (SCT). CD56 is a transmembrane glycoprotein also known as neural cell adhesion molecule 1 (NCAM-1).

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Synonym:	CD56-enriched donor cells CD56-enriched donor lymphocytes CD56+/CD3+ donor cells

CD56-enriched CD3-positive donor lymphocytes

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