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CENP-E inhibitor GSK-923295A

A small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), with potential antineoplastic activity. Upon administration, GSK-923295A binds to and inhibits CENP-E, thereby preventing cell division, inducing cell cycle arrest, and ultimately leading to an inhibition of cell proliferation. CENP-E, a kinetochore-associated mitotic kinesin, plays an essential role in chromosome movement during mitosis and regulates cell-cycle transition from metaphase to anaphase.

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Synonym:	centromere-associated protein E inhibitor GSK-923295
Code name:	GSK 923295 GSK 923295A GSK-923295 GSK-923295A GSK923295 GSK923295A

CENP-E inhibitor GSK-923295A

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