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chlorambucil

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An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.

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Synonym:	aminochlorambucil chlorambucilum chloraminophen Chlorbutin chlorbutine chlorbutinum chloroambucil chlorobutin chlorobutine Ecloril Elcoril Leukersan leukoran Lympholysin phenylbutyric acid nitrogen mustard
US brand name:	Leukeran
Foreign brand name:	Alti-chlorambucil Chloraminophene Linfolysin
Abbreviation:	CHL CLB
Code name:	CB-1348 WR-139013
Chemical structure:	4-[bis(2-chloroethyl)amino]benzenebutanoic acid 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- (9CI) butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl) gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid p-(N, N-di-2-chloroethyl)aminophenyl butyric acid p-N, N-di-(beta-chloroethyl)aminophenyl butyric acid para-N,N-di(b-chloroethyl)aminophenylbutyric acid