NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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cisplatin

An inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. Check for using this agent. ()

Synonym:	CACP cis-DDP cis-diamminedichloridoplatinum cis-diamminedichloro platinum (II) cis-diamminedichloroplatinum Cis-dichloroammine Platinum (II) Cismaplat Cisplatina cis-platinous diamine dichloride cis-platinum cis-platinum II cis-platinum II diamine dichloride CPDD Cysplatyna DDP PDD Peyrone's Chloride Peyrone's Salt Platinoxan platinum diamminodichloride
Foreign brand name:	Abiplatin Blastolem Briplatin Cisplatyl Citoplatino Citosin Lederplatin Metaplatin Neoplatin Placis Platamine Platiblastin Platiblastin-S Platinex Platinol- AQ Platinol-AQ VHA Plus Platiran Platistin Platosin
Abbreviation:	CDDP DDP
Chemical structure:	(SP-4-2)-diamminedichloroplatinum platinum, diaminedichloro-, cis- (8CI)