Skip to main content
An official website of the United States government

clofibrate

An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols.
US brand name:Atromid-S
Abbreviation:CFB
Chemical structure:2-(4-chlorophenoxy)-2-methylpropanoic acid ethyl ester
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
ethyl p-chlorophenoxyisobyturate
NSC code:79389
Search NCI's Drug Dictionary