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clofibrate

An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols.
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US brand name:Atromid-S
Abbreviation:CFB
Chemical structure:2-(4-chlorophenoxy)-2-methylpropanoic acid ethyl ester
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
ethyl p-chlorophenoxyisobyturate
NSC code:79389
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