clofibrate
An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols.
| US brand name: | Atromid-S |
|---|---|
| Abbreviation: | CFB |
| Chemical structure: | 2-(4-chlorophenoxy)-2-methylpropanoic acid ethyl ester ethyl 2-(4-chlorophenoxy)-2-methylpropanoate ethyl p-chlorophenoxyisobyturate |
| NSC code: | 79389 |