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codrituzumab

A humanized monoclonal antibody directed against the cell surface oncofetal protein glypican-3 (GPC3) with potential antineoplastic activity. Anti-GPC3 monoclonal antibody GC33 binds to GPC3 and triggers a host immune response against GPC3-expressing tumor cells, which may result in tumor cell death. GPC3, a heparin sulfate proteoglycan, is frequently upregulated in hepatocellular carcinoma and mesoderm-derived organs such as the liver, lungs, and kidney.

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Synonym:	anti-glypican 3 monoclonal antibody GC33
Code name:	GC-33 GC33 RG 7686 RO 5137382 RO-5137382 RO5137382

codrituzumab

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