copper Cu 64 SAR-bisPSMA
A radioconjugate composed of two human prostate-specific membrane antigen (PSMA) binding motifs linked to a SAR chelator and labeled with the positron emission tomography (PET) tracer copper Cu 64, with potential use as a tracer for PSMA-expressing tumors during positron emission tomography (PET)/computed tomography (CT). Upon administration of copper Cu 64 SAR-bisPSMA, the PSMA binding motifs target and bind to PSMA-expressing tumor cells. Upon binding, PSMA-expressing tumor cells can be detected during PET/CT imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells.
| Synonym: | 64Cu SAR-bisPSMA 64Cu-SAR-bisPSMA copper Cu 64-SAR-bisPSMA |
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