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corticosteroid-containing eye drop

A sterile ophthalmic solution containing a corticosteroid, with anti-inflammatory activity. Upon application of the corticosteroid-containing eye drop into the eye, the corticosteroid binds to cytoplasmic receptors, translocates to the nucleus and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2. This prevents the release of arachidonic acid, a precursor to prostaglandins and leukotrienes, both important mediators in the pro-inflammatory response mechanism.

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Synonym:	corticosteroid eye drop corticosteroid ophthalmic solution steroidal eye drops

corticosteroid-containing eye drop

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