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daphnetin

An orally bioavailable coumarin derivative and phytochemical extracted from Daphne species, with potential anti-inflammatory, antioxidant, neuroprotective, analgesic, antipyretic, antimalarial, antibacterial, anti-arthritic, neuroprotective, hepatoprotective, nephroprotective, and antineoplastic activities. Upon administration, daphnetin has a variety of mechanism of actions and modulates various signal transduction pathways. Daphnetin may reduce lymphedema by binding to and facilitating the removal of proteins, thereby reducing fluid retention.

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Synonym:	daphnetol
Chemical structure:	7,8-dihydroxy-2H-chromen-2-one 7,8-dihydroxycoumarin

daphnetin

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