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deflazacort

A synthetic glucocorticoid prodrug, with anti-inflammatory and immunomodulating properties. Upon administration, the active metabolite of deflazacort, 21-desacetyl deflazacort, binds to and activates tissue glucocorticoid receptors. This results in the inhibition of specific leukocyte functions and the inhibition of proinflammatory cytokine production.

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US brand name:	Emflaza
Code name:	MDL 458
Chemical structure:	11beta,21-dihydroxy-2'-methyl-5'beta-H-pregna-1,4-dieno(17,16-D)oxazole-3,20-dione 21-acetate 5'H-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11beta,16beta)-

deflazacort

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