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dendritic cell-gp100-MART-1 antigen vaccine

An autologous dendritic cell vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 antigen (a melanoma antigen recognized by T-cells); both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells.
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Synonym:gp100/Mart-1-transduced dendritic cell vaccine
Abbreviation:DC-gp100-MART-1
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