Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

dibotermin alfa

A recombinant form of human bone morphogenetic protein 2 (rhBMP-2), with potential bone remodeling and osteoinductive activities. Following administration, dibotermin alfa induces signaling cascades, which leads to osteoblast differentiation, enhancement of bone repair and formation, and improvement of re-vascularization. This promotes bone healing. BMP-2, a protein belonging to the transforming growth factor beta (TGFb) superfamily of proteins, plays a key role in bone and cartilage formation.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Synonym:diotermin
nebotermin
Abbreviation:rhBMP-2
rhBMP2
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search