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dicumarol

A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.

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Synonym:	bishydroxycoumarin dicoumarol
Chemical structure:	3,3'-methylenebis(4-hydroxy-2H-1-benzopyran-2-one)

dicumarol

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