dicumarol
A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.
| Synonym: | bishydroxycoumarin dicoumarol |
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| Chemical structure: | 3,3'-methylenebis(4-hydroxy-2H-1-benzopyran-2-one) |