dihydro-5-azacytidine
A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity.
| Abbreviation: | DHAC |
|---|---|
| Chemical structure: | 1,3,5-triazin-2(1H)-one, 4-amino-3, 6-dihydro-1-beta-D-ribofuranosyl monohydrochloride 5,6-dihydro-5-azacytidine HCl 5,6-dihydro-5-azacytidine hydrochloride |
| IND number: | 19672 |
| NSC code: | 264880 |