Skip to main content
An official website of the United States government

dinaciclib

A pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9; inhibition of CDK1 and CDK2 may result in cell cycle repression and tumor cell apoptosis.
Synonym:CDK inhibitor SCH 727965
cyclin-dependent kinase inhibitor SCH 727965
Code name:MK-7965
SCH 727965
Search NCI's Drug Dictionary