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dinutuximab

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A chimeric mouse/human monoclonal antibody with potential antineoplastic activity. Dinutuximab binds to the ganglioside GD2 and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung.
Synonym:Ch 14.18UTC
Ch14.18
dinutuximab beta
MOAB Ch14.18
monoclonal antibody Ch14.18
US brand name:Unituxin
Foreign brand name:Qarziba
Unituxin
Abbreviation:MOAB Ch14.18
IND number:4308
5748
NSC code:623408
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