diphenhydramine
A first generation antihistamine and ethanolamine with sedative and anti-allergic properties. Diphenhydramine competitively inhibits the histamine-1 (H1) receptor, thereby alleviating the symptoms caused by endogenous histamine on bronchial, capillary and gastrointestinal smooth muscles. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.
| Synonym: | Probedryl Rigidyl |
|---|---|
| US brand name: | Syntedril |
| Code name: | FAR 90X2 PM 255 S51 |
| Chemical structure: | 2-(diphenylmethoxy)-N,N-dimethylethylamine O-benzhydryldimethylaminoethanol |