diphenhydramine hydrochloride
The hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.
| US brand name: | Benadryl SK-Diphenhydramine |
|---|---|
| Foreign brand name: | Bendylate Eldadryl |
| NSC code: | 33299 |