eculizumab
A humanized monoclonal antibody directed against terminal complement protein C5. Eculizumab binds to terminal complement protein C5, thereby blocking C5 cleavage into pro-inflammatory components and blocking the complement-mediated destruction of paroxysmal nocturnal hemoglobinuria (PNH) red blood cells.
| Synonym: | alexion eculizumab biosimilar ABP 959 eculizumab biosimilar BCD-148 eculizumab biosimilar SB12 immunoglobulin, anti-(human complement C5 alpha-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide with human-mouse monoclonal 5G.1.1 light chain, dimer monoclonal antibody 5G1.1 monoclonal antibody anti-C5 |
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| US brand name: | Elizaria Soliris |
| Abbreviation: | h5G1.1 |
| Code name: | ABP 959 ABP-959 ABP959 BCD 148 BCD-148 BCD148 SB 12 SB-12 SB12 |