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edrecolomab

A murine monoclonal IgG2a antibody to tumor-associated epithelial cell adhesion molecule (EpCAM, or 17-1A) antigen. Edrecolomab attaches to EpCAM, a human cell surface glycoprotein that is found on normal epithelial cells and some tumor cells, such as those of colon and breast carcinomas. Upon binding, this agent recruits the body's immune effector cells, which may exhibit antitumor cytotoxicity.

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Synonym:	monoclonal antibody 17-1A
Foreign brand name:	Panorex
Abbreviation:	MOAB 17-1A
IND number:	2176 7053
NSC code:	377963

edrecolomab

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