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eflapegrastim

A long-acting, recombinant analog of the endogenous human granulocyte colony-stimulating factor (G-CSF) with hematopoietic activity. Similar to G-CSF, eflapegrastim binds to and activates specific cell surface receptors and stimulates neutrophil progenitor proliferation and differentiation, as well as selected neutrophil functions. Therefore, this agent may decrease the duration and incidence of chemotherapy-induced neutropenia. Eflapegrastim extends the half-life of G-CSF, allowing for administration once every 3 weeks.

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Synonym:	long-acting granulocyte colony-stimulating factor receptor SPI-2012
US brand name:	Rolontis
Abbreviation:	LAPS-GCSF
Code name:	HM10460A SPI-2012

eflapegrastim

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