Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

elacestrant hydrochloride

View Patient Information
The hydrochloride salt form of elacestrant, an orally available, selective estrogen receptor degrader (SERD), with antineoplastic activity. Upon oral administration, elacestrant acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the proteosomal degradation of the receptor. This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer cells.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Synonym:RAD-1901 dihydrochloride
RAD1901 dihydrochloride
US brand name:Orserdu
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search