eniluracil
An orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU.
| Synonym: | 5-ethynyluracil ethynyluracil |
|---|---|
| Code name: | 776C85 ADH300004 GW776 GW776C85 |
| Chemical structure: | 5-ethynyl-2,4(1H,3H)-pyrimidinedione |