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ethinyl estradiol

A semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy.
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US brand name:Estinyl
Ethinoral
Feminone
Orestralyn
Foreign brand name:Diogyn E
Eticylol
Inestra
Lynoral
Abbreviation:EE
Chemical structure:(17alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol
IND number:7259
NSC code:10973
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