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formestane

A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.

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Synonym:	4-hydroxyandrostenedione
Foreign brand name:	Lentaron
Abbreviation:	4-OHA 4-OHAD
Code name:	CGP-32349
Chemical structure:	4-Hydroxyandrost-4-ene-3,17-dione

formestane

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