Skip to main content
An official website of the United States government

fosfestrol

The diphosphate ester of a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.
Synonym:diethyldihydroxystilbene diphosphate
diethylstilbestrol diphosphate
diethylstilbestryl diphosphate
fosfestrol sodium phosphoestrolum
stilbestrol diphosphate
stilboestrol diphosphate
US brand name:Stilphostrol
Foreign brand name:Honvan
Honvol
ST-52
Abbreviation:DESP
Chemical structure:(E)-4,4'-(1,2-ethenediyl)-bisphenol bis(dihydrogen phosphate)
alpha,alpha'-diethyl-4,4'-stilbenediol diphosphoric acid ester
diethylstilbestrol 4,4'-diphosphoric ester
Search NCI's Drug Dictionary