gadolinium-based contrast agent BAY1747846

A gadolinium (Gd)-based contrast agent (GBCA) that can potentially be used for contrast-enhanced MRI (CE-MRI). Upon intravenous administration of GBCA BAY1747846, and upon placement in a magnetic field, this agent produces a large magnetic moment and creates a large local magnetic field, which can enhance the relaxation rate of nearby protons. This change in proton relaxation dynamics increases the MRI signal intensity of tissues in which this agent has accumulated due to abnormal vascularity and altered perfusion. This allows for enhanced contrast and visualization of those tissues compared to unenhanced MRI.