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gallium Ga 68-EVS459

A radioconjugate composed of EVS459, a folate receptor alpha (FRa; FolRa; FOLR1)-targeting moiety, radiolabeled with gallium Ga 68 (68Ga), with potential imaging activity upon positron emission tomography/computed tomography (PET/CT) or PET/magnetic resonance imaging (MRI). Upon administration of gallium Ga 68-EVS459, the FOLR1-targeting moiety targets and binds to FOLR1 expressed on tumor cells. Upon PET/CT or PET/MRI imaging, FOLR1-expressing tumor cells can be visualized. FOLR1 is a glycosylphosphatidylinositol linked cell-surface glycoprotein that is widely expressed in certain cancers while its expression is limited in normal tissues.
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Synonym:[68Ga]-EVS459
[68Ga]Ga-EVS459
68Ga-EVS459
gallium Ga 68 EVS459
gallium Ga 68-EVS-459
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