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gallium Ga 68-NeoB

A radioconjugate consisting of a gastrin-releasing peptide receptor (GRPR) antagonist linked via the chelating agent, dodecanetetraacetic acid (DOTA), to the beta-emitting radioisotope gallium Ga 68, with potential use in diagnostic imaging using positron emission tomography/computed tomography (PET/CT). Upon administration, gallium Ga 68-NeoB binds to GRPRs present on cancer cells. Upon binding, this radioconjugate can be used to quantify tumor uptake of NeoBOMB1 using PET/CT. GRPR, also known as bombesin receptor subtype 2, is a G protein-coupled receptor that is overexpressed in some cancer types.
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Synonym:[68Ga]-NeoB
68Ga-DOTA-NeoBOMB1
68Ga-NeoB
gallium Ga 68 NeoBOMB1
gallium-68 DOTA-NeoBOMB1
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