Skip to main content
An official website of the United States government
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

gallium Ga 68 NY104

A radioconjugate composed of NY104, a small molecule carbonic anhydrase IX (CAIX; carbonic anhydrase 9; CA9; G250)-targeting tracer comprised of an acetazolamide core, a hydrophilic spacer and the bifunctional, macrocyclic chelating agent 1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA), labeled with the radionuclide gallium Ga 68, with potential use as a tracer for CAIX-expressing tumor cells during positron emission tomography (PET). Upon administration of gallium Ga 68 NY104, the NY104 moiety targets and binds to CAIX-expressing tumor cells. Upon binding, CAIX-expressing tumor cells can be detected during PET. CAIX, a member of the carbonic anhydrase family and a tumor-associated antigen (TAA), is found in a majority of renal cell carcinomas while absent in most normal tissues.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Synonym:68Ga-NY104
68Ga-NYM005
gallium Ga 68 NYM005
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search