gallium Ga 68 P3
A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting ligand, P3, labeled with the radioisotope gallium Ga 68, with potential use as a tracer for PSMA-expressing tumors during positron emission tomography (PET). Upon intravenous administration of gallium Ga 68 P3, the P3 moiety targets and binds to PSMA-expressing tumor cells. Upon binding, PSMA-expressing tumor cells can be detected during PET imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells as well as a variety of other solid tumors.
| Synonym: | [68Ga]-P3 [68Ga]P3 68Ga-P3 ERK inhibitor D3S-002 |
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| Code name: | D3S 002 D3S-002 D3S002 |