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ganciclovir

A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears to inhibit viral DNA synthesis by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation.

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Synonym:	BW 759U BW-B759U Nordeoxyguanosine
Foreign brand name:	Cymevan Virgan
Abbreviation:	2'NDG BW-B759U DHPG
Chemical structure:	2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one 2'-Nor-2'-deoxyguanosine 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine

ganciclovir

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