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ganciclovir

A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears to inhibit viral DNA synthesis by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation.
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Synonym:BW 759U
BW-B759U
Nordeoxyguanosine
Foreign brand name:Cymevan
Virgan
Abbreviation:2'NDG
BW-B759U
DHPG
Chemical structure:2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one
2'-Nor-2'-deoxyguanosine
9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine
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