girentuximab
A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, girentuximab may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents.
Synonym: | chimeric monoclonal antibody cG250 monoclonal antibody G-250 WX-G250 |
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US brand name: | Rencarex |
Abbreviation: | cG250 MOAB G250 |