Skip to main content

Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

golnerminogene pradenovec

A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF.

Check for active clinical trials using this agent View this agent in the NCI Thesaurus

Synonym:	adenovirus 5-tumor necrosis factor alpha AdGV11-TNFalpha tumor necrosis factor adenovirus 5 vector
US brand name:	TNFerade
Abbreviation:	Ad 5-TNF Alpha Ad5-TNFa
Code name:	ADgv EGR.TNF.11D

golnerminogene pradenovec

Search NCI's Drug Dictionary