gridegalutamide
An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon administration, gridegalutamide causes degradation of AR, prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).
| Synonym: | Androgen Receptor Degrader CC-94676 AR degrader CC-94676 |
|---|---|
| Code name: | BMS 986365 BMS 986409 BMS-986365 BMS-986409 BMS986365 BMS986409 CC 1083611 CC 94676 CC-1083611 CC-94676 CC1083611 CC94676 CEL 010355 CEL-010355 CEL010355 |