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HPV6/11-targeted DNA plasmid vaccine INO-3107

A DNA vaccine consisting of plasmids encoding E6 and E7 genes of human papilloma virus subtype 6 (HPV-6) and 11 (HPV-11), with potential immunostimulating and antineoplastic activities. Upon administration via intramuscular electroporation, the HPV-6/11-targeted DNA plasmid vaccine INO-3107 expresses the HPV-6/11 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing HPV6 and/or HPV11 E6 and E7 proteins, resulting in tumor cell lysis. HPV-6/11 infections are associated with aerodigestive malignancies.
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Synonym:HPV-6/11-targeting immunotherapeutic vaccine INO-3107
HPV6/11-targeted DNA plasmid immunotherapeutic INO-3107
Code name:INO 3107
INO-3107
INO3107
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